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Mildronate is a structural analogue of a precursor of carnitine - gamma-butyrobetaine

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Mildronat is a medication. This product is purchasable in form of gel or cream, tablets, capsules, powder, liquid for injection. Capsules of this preparation can contain 250 or 500 mg. Its chemical structure is following: 3-(2, 2, 2-Trimetilgidraziny) propionate.
This drug has got many functions. It prevents accumulation of activated forms of oxygenated fatty acids, increases cellular and humoral immunities, provides vazodilation and activates glikoliz. This medication may diminish psychological and physical stress. So, this medication possesses also tonic effects. That's why mildronat is also utilized during mental and physical recovery.

Administration of mildronat
Mildronat is used in medicine as anti-ischemic and anti-stress drug for treatment of patients that have got different cardiovascular diseases. This medicine is recommended in order to treat people who have got angina, chronic heart failure, myocardial infarction, cardialgia, acute and chronic violations of cerebral circulation, bleeding in the retina of various etiology, thrombosis central retinal vein and its branches, retinopathy of different etiology (diabetic, hypertension); abstinence syndrome in chronic alcoholism, reduction of efficiency and physical longevity.
This preparation is administrated alone or in combination with other specific drugs or certain medical therapies.

Dosage of mildronat
Mildronat should be utilized 30 minutes after food. The recommended dosage of this medication depends on some factors. It can depend on kind of illness, its severity and some other medical conditions.
If you administrate this drug by mouth, it is usually prescribed to take 250 mg 3 times a day for 3-4 days. Then the measure should be decreased.
Use this drug as prescribed by your medic.
There were no reported any cases of overdose.

Mildronat and alcoholic cardiomyopathy
It is known about a research related to mildronat that was leaded in Moscow. The goal of the research was to display the effectiveness of this preparation. More than 150 people who had alcoholic cardiomyopathy were enrolled in the research. The average age was 50 years. The persons were utilizing 500 mg of mildronat twice daily by injection for 3 days and then they were using 250 mg of this medication orally for 27 days. The whole therapy lasted a month. The results of the treatment were following:
- reduction of shortness of breath by 27%;
- decreasing of the frequency of paroxysmal disorders of heart rhythm by 20%;
- decreasing of the concentration of C-reactive protein by 17%.

So, the results showed that mildronat could decrease the frequency of arrhythmic episodes in persons who suffered of paroxysmal cardiac arrhythmia. It was displayed that this preparation also decreased dyspnea and improved the quality of life in people that had alcoholic cardiomyopathy.

Undesirable results of Mildronat
Mildronat, as other products, can cause some negative results. Possible side reactions of this product are following: dyspeptic disturbances, tachycardia, changes in arterial pressure, headache, agitation, weakness and eosinophylia. It doesn't mean that all people that take this drug will suffer of these results but you have to know that they may appear. Some patients may suffer of allergic reactions, when they utilize this preparation. If you note some allergic reactions, consult your prescriber. Moreover, if you observe some negative symptoms that are not written above, consult your doctor. If you have questions about side reactions, discuss to your specialist.
Before administrating this product, tell to your pharmacist about all medicines that you use.

Cautions
Do not utilize Mildronate, if you observe that you suffer of allergy to mildronate or any of the other substances of this drug. It is banned to utilize this product in cases which are written below:
- if you are pregnant;
- if you intend to become pregnant;
- if you are breast feeding.

It is dangerous to administrate mildronat during pregnancy. It can have negative influence on mother's organism and unborn kid. In order to prevent these undesirable results do not take this product, if you are pregnant.
If you are breast feeding, there is a probability that some substances of this medication can be excreted in breast milk due to using mildronat. Nobody knows whether it may happen. That's why do not utilize this medication in order to escape from unpleasant consequences. If you have to be cured with mildronat, cease breast feeding.

Interaction with other products
Sometimes mildronat is administrated in combination with some other preparations. It may be combined with antianginal medicines, anticoagulants, antiagregants, antarrhythmic drugs, cardiac glycosides, diuretics etc. It is recommended to tell to your doctor about all products which you use, before using mildronat.

Keeping
Store out of the reach of kids.
Keep out of warmness. It's banned to keep the medication in the bathroom, near the kitchen sink, or in other moist spaces. Do not store outdated drugs. Be certain that any unneeded preparation is away from the reach of kids.
It is not allowed to share Mildronat with others.

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